It has been a quiet period for new scientific information despite much happening with Omicron - which has now been detected in over 130 countries and is the dominant variant in several (including South Africa, Denmark, UK, Japan, India, Australia, France, USA). It is reported that case numbers have declined in South Africa sufficiently for them to consider the Omicron wave over, and there are possible signs of a plateau beginning in UK. Despite very high case numbers in the worst affected countries, the pattern with hospitalisations is less consistent. In the USA there have been calls for consideration of hospitalisation numbers as the prime statistic rather than case numbers (which reached 1 million in one day). Those regions with very high case numbers also are experiencing enormous levels of work absence due to isolation of close contacts, which strains health systems as well as the airline industry. In some locations, systems and equipment for COVID testing are struggling to meet demand.